RAF Typhoon FGR4s have operated alongside French warplanes in a combined operation targeting an subterranean weapons facility in Syria used by the IS group, per a report from the UK's MoD.
The site, pinpointed through intelligence, was assessed as containing munitions and bombs, the announcement noted, and was situated in hills just above Palmyra in central Syria.
"Our fighter planes employed precision-guided Paveway IV munitions to strike a several approach shafts down to the facility... preliminary assessments indicate the objective was successfully hit," the ministry announced.
There was no evidence of any civilian casualties in the strike late on Saturday and all the aircraft returned to base without incident, the defence officials confirmed.
The British jets were supported by a Voyager tanker plane.
Daesh - referred to as ISIS - established jihadist rule over parts of Syria and Iraq prior to its 2019 collapse.
"This strike shows British leadership, and commitment to operate in unison with our partners, to eradicate any re-emergence of the terrorist group and their violent and radical beliefs in the Middle East," Britain's Defence Chief the minister said.
RAF aircraft have performed patrols over Syria to "forestall any attempted comeback" of the group following its military defeat at the Baghuz confrontation in 2019, the MoD reported.
"I extend gratitude to the personnel of our armed forces who took part in this mission for their skill and their courage," the Defence Secretary commented. "Including them were a great many British troops stationed over the festive period. This operation, to eliminate terrorist threats who endanger our safety, highlights how British military are ready to step up, throughout the year, ensuring Britain's security domestically and strong abroad."
In December, the American forces carried out what it called a "large-scale strike" on IS targets in the country, subsequent to an ambush killed two US troops and a civilian linguist in Palmyra.
The UN says IS still maintains an estimated 5,000 to 7,000 fighters in Iraq and Syria.
